CDKN3 Rabbit Polyclonal Antibody

CAT#: TA327249

CDKN3 Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts of mouse heart cell line, using CDKN3 antibody.

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  Immunofluorescence analysis of MCF7 cell using CDKN3 antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: ICC/IF, IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200;IF 1:50- 1:200
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human CDKN3
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: cyclin-dependent kinase inhibitor 3
• Database Link:
  NP_005183
  Entrez Gene 72391 MouseEntrez Gene 1033 Human
  UniProt ID Q16667
• Background: The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
• Synonyms: CDI1; CIP2; KAP; KAP1

Reference Data

• Protein Families: Druggable Genome, Phosphatase