alpha 1 Glycine Receptor (GLRA1) Rabbit Polyclonal Antibody

CAT#: TA327455

Rabbit anti-GLRA1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using GLRA1 antibody. (1: Hela cell lysate 2: Mouse brain tissue lysate)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide of human GLRA1
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: glycine receptor alpha 1
• Database Link:
  NP_000162
  Entrez Gene 14654 MouseEntrez Gene 25674 RatEntrez Gene 2741 Human
  UniProt ID P23415
• Background: Glycine receptor subunit alpha-1 is a protein that in humans is encoded by the GLRA1 gene. The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different isoforms have been found for this gene.
• Synonyms: HKPX1; STHE

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction