MC2 receptor (MC2R) Rabbit Polyclonal Antibody

CAT#: TA327478

Rabbit anti-MC2R Polyclonal Antibody

Product Images

Western blot analysis of extracts of 293 cell lysate, using MC2R antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 1:1000 - 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide of human MC2R.
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 34 kDa
• Gene Name: melanocortin 2 receptor
• Database Link:
  NP_000520
  Entrez Gene 17200 MouseEntrez Gene 282839 RatEntrez Gene 4158 Human
  UniProt ID Q01718
• Background: MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.
• Synonyms: ACTHR

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction