EMA (MUC1) Mouse Monoclonal Antibody [Clone ID: E29]

CAT#: TA327672

Mouse Monoclonal EMA Antibody

Product Images

Immunohistochemistry staining of Paraffin Breast tissue by EMA antibody (dilution: 1:100 - 1:500; visualization of staining: Cytoplasmic, membranous)

Specifications

Product Data

• Clone Name: E29
• Applications: IHC
• Recommended Dilution: IHC: 1:100 - 1:500
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a, kappa
• Clonality: Monoclonal
• Formulation: This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: mucin 1, cell surface associated
• Database Link:
  NP_002447
  Entrez Gene 4582 Human
  UniProt ID P15941
• Synonyms: ADMCKD; ADMCKD1; CA 15-3; CD227; EMA; H23AG; KL-6; MAM6; MCD; MCKD; MCKD1; MUC-1; SEC
• Note: Anti-EMA is a useful marker for staining many carcinomas. It stains normal and neoplastic cells from various tissues, including mammary epithelium, sweat glands, and squamous epithelium. Hepatocellular carcinoma, adrenal carcinoma, and embryonal carcinomas are consistently EMA negative, so keratin positivity with negative EMA favors one of these tumors. Anti-EMA is frequently positive in meningioma, which can be useful when distinguishing it from other intracranial neoplasms, e.g. Schwannomas.

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane