Cadherin 16 (CDH16) Mouse Monoclonal Antibody [Clone ID: MRQ-33]

CAT#: TA327696

Mouse Monoclonal ksp- Cadherin Antibody

Product Images

Immunohistochemistry staining of Paraffin Kidney tissue by ksp- Cadherin antibody (dilution: 1:100 - 1:500; visualization of staining: Membranous, cytoplasmic)

Specifications

Product Data

• Clone Name: MRQ-33
• Applications: IHC
• Recommended Dilution: IHC: 1:100 - 1:500
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Formulation: This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: cadherin 16
• Database Link:
  NP_001191673
  Entrez Gene 1014 Human
  UniProt ID O75309
• Synonyms: KSP-cadherin
• Note: Kidney-specific cadherin (Ksp-cadherin or cadherin-16) is a kidney-specific member of the cadherin family of cell adhesion molecules. Within the kidney, Ksp-cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Recent studies have shown that anti- Ksp-cadherin can be used to distinguish chromophobe renal cell carcinoma from oncocytoma with a membranous staining pattern in 96% of chromophobe carcinomas, but in only 6% of oncocytomas. However, other studies report anti-Ksp-cadherin positivity in 100% of chromophobe RCCs, and 95% of oncocytomas.

Reference Data

• Protein Families: Transmembrane