NAPSIN A (NAPSA) Rabbit Polyclonal Antibody

CAT#: TA327711

Rabbit Polyclonal Napsin A Antibody

Product Images

Immunohistochemistry staining of Paraffin Lung adenocarcinoma, kidney tissue by Napsin A antibody (dilution: 1:100 - 1:500; visualization of staining: Cytoplasmic)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 1:100 - 1:500
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Formulation: This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: napsin A aspartic peptidase
• Database Link:
  NP_004842
  Entrez Gene 9476 Human
  UniProt ID O96009
• Synonyms: KAP; Kdap; NAP1; NAPA; SNAPA
• Note: Napsin is a pepsin-like aspartic proteinase, in the A1 clan of the AA clade of proteinases. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein with the molecular weight of approximately 38 kDa. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Lysosome