STAT3 Mouse Monoclonal Antibody [Clone ID: 13A3-1]

CAT#: TA328065

Mouse Monoclonal anti-STAT3 Phospho (Tyr705) Antibody

Product Images

HepG2 cell extracts were resloved by electrophoresis, transferred to nitrocellulose, and probed with purified anti-STAT3 pY705 (clone 13A3-1) antibody. Proteins were visualized using an anti-mouse IgG secondary antibody conjugated to HRP and chemiluminescence detection. Lane 1, lysates from untreated HepG2 cells; Lane 2, lysates from HepG2 cells treated with recombinant hIL-6 for 15 minutes.

Specifications

Product Data

• Clone Name: 13A3-1
• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: KLH conjugated modified synthetic peptide
• Formulation: This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.05% sodium azide.
• Concentration: lot specific
• Purification: The antibody was purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 88 kD
• Gene Name: signal transducer and activator of transcription 3
• Database Link:
  NP_998827
  Entrez Gene 6774 Human
  UniProt ID P40763
• Background: Tyrosine phosphorylation of STAT3 at Y705 occurs in response to LIF, IL-6, leptin, OSM, EGF, PDGF, and HGF. It plays a key role in cell growth and apoptosis through mediating expression of a variety of genes in response to the stimuli.
• Synonyms: ADMIO; APRF; HIES

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Acute myeloid leukemia, Adipocytokine signaling pathway, Chemokine signaling pathway, Jak-STAT signaling pathway, Pancreatic cancer, Pathways in cancer