Junctional Adhesion Molecule C (JAM3) Rabbit Polyclonal Antibody

CAT#: TA328124

Rabbit polyclonal anti-JAM3 antibody (C-term)

Product Images

Western blot analysis of lysates from human placenta, mouse brain and rat brain tissue (from left to right), using JAM3 Antibody (C-term) (Cat. #TA328124). TA328124 was diluted at 1:1000 at each lane. A goat anti-rabbit (HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This JAM3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 261-295 amino acids from the C-terminal region of human JAM3.
• Formulation: PBS with 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: junctional adhesion molecule 3
• Database Link:
  NP_116190
  Entrez Gene 83964 MouseEntrez Gene 315509 RatEntrez Gene 83700 Human
  UniProt ID Q9BX67
• Background: Participates in cell-cell adhesion. It is a counter- receptor for ITGAM, mediating leukocyte-platelet interactions and is involved in the regulation of transepithelial migration of polymorphonuclear neutrophils (PMN). The soluble form is a mediator of angiogenesis.
• Synonyms: JAM-2; JAM-3; JAM-C; JAMC

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Epithelial cell signaling in Helicobacter pylori infection, Leukocyte transendothelial migration, Tight junction