TRAIL (TNFSF10) Rabbit Polyclonal Antibody

CAT#: TA328462

Anti-Human sTRAIL/Apo2L Rabbit Polyclonal Antibody

Product Images

This antibody stained formalin-fixed, paraffin-embedded sections of human metastatic carcinoma of lymph node from breast tissue. The recommended concentration is 0.25 ug/ml with an overnight incubation at 4C. An HRP-labeled polymer detection system was used with a DAB chromogen. Heat induced antigen retrieval with a pH 6.0 Sodium Citrate buffer is recommended. Optimal concentrations and conditions may vary.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: WB: 0.1-0.2ug/mL, ELISA: 0.25-2ug/mL, IHC: 0.25ug/mL - 1mg/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: E.coli derived Recombinant Human sTRAIL/Apo2L
• Formulation: A sterile filtered antibody solution was lyophilized from PBS, pH 7.2.
• Purification: Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hsTRAIL/Apo2L. Anti-Human sTRAIL/Apo2L specific antibody was purified by affinity chromatography employing immobilized hsTRAIL/Apo2L matrix.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: tumor necrosis factor superfamily member 10
• Database Link:
  NP_003801
  Entrez Gene 8743 Human
  UniProt ID P50591
• Synonyms: Apo-2L; APO2L; CD253; TL2; TRAIL
• Note: Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of Human sTRAIL/Apo2L (10.0 ng/ml), a concentration of 150 ng/ml of this antibody is required.

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Apoptosis, Cytokine-cytokine receptor interaction, Natural killer cell mediated cytotoxicity