FBXO7 Rabbit Polyclonal Antibody

CAT#: TA329827

Rabbit Polyclonal Anti-FBXO7 Antibody

Product Images

FBXO7 antibody - middle region validated by WB using U2OS cells at 0.5ug/ml.

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  WB Suggested Anti-FBXO7 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: MCF7 cell lysateFBXO7 is supported by BioGPS gene expression data to be expressed in MCF7

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  Immunoprecipitation -- 5ug antibody

Specifications

Product Data

• Applications: IP, WB
• Recommended Dilution: WB, IP
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-FBXO7 antibody: synthetic peptide directed towards the middle region of human FBXO7. Synthetic peptide located within the following region: PGETPSQFPPLRPRFDPVGPLPGPNPILPGRGGPNDRFPFRPSRGRPTDG
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 58 kDa
• Gene Name: F-box protein 7
• Database Link:
  NP_001028196
  Entrez Gene 25793 Human
  UniProt ID Q9Y3I1
• Background: FBXO7 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO7 belongs to the Fbxs class and it may play a role in regulation of hematopoiesis.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.
• Synonyms: FBX; FBX07; FBX7; PARK15; PKPS
• Note: Immunogen sequence homology: Dog: 100%; Human: 100%; Bovine: 100%; Rabbit: 100%; Pig: 93%; Rat: 93%; Horse: 92%; Mouse: 92%; Zebrafish: 83%; Guinea pig: 83%

Reference Data

• Protein Families: Druggable Genome