SFTPC Rabbit Polyclonal Antibody
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beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
USD 159.00
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Specifications
Product Data | |
Applications | ICC/IF, IHC, WB |
Recommended Dilution | WB 1:500 - 1:2000;IHC 1:50 - 1:200;IF 1:50 - 1:200 |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human SFTPC |
Formulation | Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 197 |
Gene Name | surfactant protein C |
Database Link | |
Background | This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified. |
Synonyms | BRICD6; PSP-C; SFTP2; SMDP2; SP-C |
Reference Data | |
Protein Families | Secreted Protein, Transmembrane |
Documents
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.