G0 Protein alpha (GNAO1) Rabbit Polyclonal Antibody
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Other products for "GNAO1"
Specifications
Product Data | |
Applications | ICC/IF, WB |
Recommended Dilution | WB 1:500 - 1:2000 |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human GNAO1 |
Formulation | Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 354 |
Gene Name | G protein subunit alpha o1 |
Database Link | |
Background | Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. Each G protein contains an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand-receptor binding results in detachment of the G protein, switching it to an 'on' state and permitting Galpha activation of second messenger signalling cascades. There are several types of Galpha proteins; Galphas and Galphai bind directly to adenylyl cyclase and stimulate or inhibit its activity, leading to an increase or decrease in cAMP levels respectively. |
Synonyms | EIEE17; G-ALPHA-o; GNAO; HLA-DQB1 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Long-term depression, Melanogenesis |
Documents
Product Manuals |
FAQs |
SDS |
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