CHRNB1 Rabbit Polyclonal Antibody

CAT#: TA332588

Rabbit anti-CHRNB1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using CHRNB1 antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 1:500 - 1:2000, IHC 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human CHRNB1
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 501
• Gene Name: cholinergic receptor nicotinic beta 1 subunit
• Database Link:
  NP_000738
  Entrez Gene 11443 MouseEntrez Gene 24261 RatEntrez Gene 1140 Human
  UniProt ID P11230
• Background: The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.
• Synonyms: ACHRB; CHRNB; CMS1D; CMS2A; CMS2C; SCCMS

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane