GDNF Receptor alpha 1 (GFRA1) Rabbit Polyclonal Antibody
Frequently bought together (2)
Transient overexpression lysate of GDNF family receptor alpha 1 (GFRA1), transcript variant 2
USD 396.00
Other products for "GDNF Receptor alpha 1"
Specifications
Product Data | |
Applications | IF, WB |
Recommended Dilution | WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200 |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human GFRA1 |
Formulation | Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 465 |
Gene Name | GDNF family receptor alpha 1 |
Database Link | |
Background | Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. |
Synonyms | GDNFR; GDNFRA; GFR-ALPHA-1; RET1L; RETL1; TRNR1 |
Reference Data | |
Protein Families | Druggable Genome |
Documents
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