ATP7B Rabbit Polyclonal Antibody

CAT#: TA332835

Rabbit anti-ATP7B Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using ATP7B antibody.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human ATP7B
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 1465
• Gene Name: ATPase copper transporting beta
• Database Link:
  NP_000044
  Entrez Gene 11979 MouseEntrez Gene 24218 RatEntrez Gene 540 Human
  UniProt ID P35670
• Background: This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
• Synonyms: PWD; WC1; WD; WND

Reference Data

• Protein Families: Druggable Genome, Transmembrane