GST3 (GSTP1) Rabbit Polyclonal Antibody

CAT#: TA332845

Rabbit anti-GSTP1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using GSTP1 antibody.

• 

  Immunohistochemistry of paraffin-embedded human liver cancer using GSTP1 antibody at dilution of 1:200 (400x lens).

• 

  Immunohistochemistry of paraffin-embedded mouse kidney using GSTP1 antibody at dilution of 1:200 (400x lens).

Specifications

Product Data

• Applications: ICC/IF, IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50 - 1:200;IF 1:50 - 1:200
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human GSTP1
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 23 kDa
• Gene Name: glutathione S-transferase pi 1
• Database Link:
  NP_000843
  Entrez Gene 14870 MouseEntrez Gene 2950 Human
  UniProt ID P09211
• Background: Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
• Synonyms: DFN7; FAEES3; GST3; GSTP; HEL-S-22; PI

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, Prostate cancer