Camk2a Rabbit Polyclonal Antibody

CAT#: TA333121

Phospho-Camk2a-T286 Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts from 293 cells using Phospho-Camk2a-Thr286 antibody.

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: WB,1:2000 - 1:4000
  ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Formulation: Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 54kDa
• Gene Name: calcium/calmodulin-dependent protein kinase II alpha
• Database Link:
  NP_033922
  Entrez Gene 815 HumanEntrez Gene 25400 RatEntrez Gene 12322 Mouse
  UniProt ID P11798
• Background: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene.
• Synonyms: CAMKA; CaMKIINalpha; KIAA0968