KCNA5 Rabbit Polyclonal Antibody

CAT#: TA334713

Rabbit Polyclonal Anti-KCNA5 Antibody

Product Images

WB Suggested Anti-KCNA5 Antibody; Titration: 1.0 ug/ml; Positive Control: HepG2 Whole Cell

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-KCNA5 antibody: synthetic peptide directed towards the N terminal of human KCNA5. Synthetic peptide located within the following region: DPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALGTASLHHQR
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 67 kDa
• Gene Name: potassium voltage-gated channel subfamily A member 5
• Database Link:
  NP_002225
  Entrez Gene 3741 Human
  UniProt ID P22460
• Background: Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). KCNA5 encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion.
• Synonyms: ATFB7; HCK1; HK2; HPCN1; KV1.5; PCN1
• Note: Immunogen Sequence Homology: Human: 100%; Rat: 93%; Mouse: 93%

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane