MSI1 Rabbit Polyclonal Antibody
Other products for "MSI1"
Specifications
Product Data | |
Applications | IF, WB |
Recommended Dilution | WB: 1:500, IHC: 1:10-1:500, IHC-P: 1:10-1:500 |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Reacts with residues 5-21 [APQPGLASPDSPHDPCK] of the human, mouse and rat Musashi 1 protein. |
Formulation | PBS, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Concentration | lot specific |
Purification | Immunogen affinity purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | musashi RNA binding protein 1 |
Database Link | |
Background | Musashi1, a neural RNA-binding protein, plays an important role in regulating cell differentiation in precursor cells. Musashi-1 (Msi-1) has been shown to increase the accumulation of tau isoforms in intracellular inclusions in dementia. It may play a role in the pathogenesis of various neurodegenerative disorders. Musashi1 has also been detected in human tumor tissues such as gliomas and melanomas, suggesting its involvement in cancer development. Msi-1 also appears to play be an vital role in the development of several types of carcinoma such as human hepatoma, and may be a useful molecular marker for tumor detection. |
Synonyms | musashi 1; musashi homolog 1 (Drosophila) |
Note | Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID 24006477) |
Reference Data |
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