MYD88 Rabbit Polyclonal Antibody

CAT#: TA336449

Rabbit Polyclonal MyD88 Antibody


USD 424.00

5 Days*

Size
    • 100 ug

Product Images

Frequently bought together (3)
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Specifications

Product Data
Applications WB
Recommended Dilution Immunocytochemistry/ Immunofluorescence: 1:100, Immunohistochemistry-Paraffin: 2-5 ug/ml, Immunohistochemistry: 2-5 ug/ml, Western Blot: 0.5-2 ug/ml
Reactivities Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen A peptide corresponding to amino acid residues 233-248 of human MyD88.
Formulation PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration lot specific
Purification Protein G purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name myeloid differentiation primary response 88
Background MyD88, a protein involved in interleukin-1 (IL-1) mediated signalling was originally isolated as myeloid differentiation primary response gene (3,4). MyD88 possesses a N-terminal death domain similar to cytoplasmic segments of TNF receptor 1, Fas, and C-terminal region related to IL-1 and Toll receptors. Overexpression of MyD88 induces activation the c-Jun N-terminal kinase and NF-kB through its death domain (1,2). The C-terminus of MyD88 interacts with the IL-1 receptor and blocks NF-kB activation induced by IL-1, but not by NF-kB.
Synonyms MYD88D
Reference Data
Protein Families Druggable Genome
Protein Pathways Apoptosis, Toll-like receptor signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.