Tnk1 Rabbit Polyclonal Antibody
Other products for "Tnk1"
Specifications
Product Data | |
Applications | IF, WB |
Recommended Dilution | WB: 1:500-1:1000, IF: 1:50-1:200 |
Reactivities | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | C-terminal residues 421-434 [QNQVQSLPAGSAEP] of the 47 kDa mouse Kos1 / Tnk1 protein. |
Formulation | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Concentration | lot specific |
Purification | Immunogen affinity purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | tyrosine kinase, non-receptor, 1 |
Database Link | |
Background | Kinase of embryonic stem cells (Kos1) is a nonreceptor protein tyrosine kinase (NRPTK) and a new member of the Ack family of NRPTKs. Kos1 is a ubiquitously expressed 47-kDa protein with autotyrosine kinase activity that is developmentally regulated during embryogenesis. Kos1 is also upregulated following IL3 withdrawal from factor-dependent murine NSF/N1.H7 cells that undergo apoptosis, suggesting a role in growth inhibition. Data support a negative regulatory role for Kos1 in regulating the Ras-Raf1-MAPK growth pathway by a mechanism that requires its autotyrosine kinase activity. |
Synonyms | MGC46193 |
Note | This antibody may be used for Western blot and immunocytochemistry/immunofluorescence. |
Reference Data |
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