Cathepsin B (CTSB) Rabbit Polyclonal Antibody

CAT#: TA336744

Rabbit Polyclonal Cathepsin B Antibody

Product Images

Western Blot: Cathepsin B Antibody TA336744 - extracts from COLO cells.

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  Immunohistochemistry-Paraffin: Cathepsin B Antibody TA336744 - Human brain tissue.

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  Immunohistochemistry-Paraffin: Cathepsin B Antibody TA336744 - Staining for Cathepsin B in mouse ureter.

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  Immunocytochemistry/Immunofluorescence: Cathepsin B Antibody TA336744 - Cathespin B antibody was tested at 1:50 in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). Puncta staining

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1.0 - 2.0 ug/ml, IF: 1:50 - 1:100, IHC: 1:200, IHC-P: 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide made to an internal portion of the human NFkB p65 protein (between residues 200-270) [UniProt P07858]
• Formulation: PBS, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: cathepsin B
• Database Link:
  NP_680093
  Entrez Gene 13030 MouseEntrez Gene 64529 RatEntrez Gene 1508 Human
  UniProt ID P07858
• Background: The cathepsin protease family contains several diverse classes of enzymes. Cathepsins B, L, H, K, S and O are part of the cysteine protease class. Cathepsin B is a dimer consisting of a heavy chain and a light chain cross-linked by a disulfide bond and is a lysosomal cysteine protease. Cathepsin B is expressed in luminal epithelial cells and its expression indicates that Cathepsin B is a marker for secretory cell death. Cathepsin B also participates in intracellular degradation and turnover of proteins.
• Synonyms: APPS; CPSB

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Antigen processing and presentation, Lysosome