CRLF2 Mouse Monoclonal Antibody [Clone ID: 59N5G4]

CAT#: TA337156

Mouse Monoclonal TSLP R/CRLF2 Antibody (59N5G4)

Product Images

Immunohistochemistry-Paraffin: TSLP R/CRLF2 Antibody (59N5G4) TA337156 - Formalin-fixed, paraffin-embedded normal human kidney tissue stained with TSLPR antibody (5 ug/ml), peroxidase-conjugate and DAB chromogen.

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  Western Blot: TSLP R/CRLF2 Antibody (59N5G4) TA337156 - Analysis of CRLF2 in an A) partial recombinant protein (0.1 ug/ml), B) human muscle and C) liver lysate (5 ug/ml) using CRLF2 antibody.

Specifications

Product Data

• Clone Name: 59N5G4
• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry, Western Blot: 1:100-1:2000, Immunohistochemistry-Paraffin
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Immunogen: Amino acids 119-231 of human TSLPR protein were used as the immunogen for the antibody.
• Formulation: PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Protein G purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: cytokine receptor-like factor 2
• Database Link:
  NP_071431
  Entrez Gene 64109 Human
  UniProt ID Q9HC73
• Background: TSLPR is a member of the hematopoietin receptor family which acts as a receptor for the cytokine thymic stromal lymphopoietin (TSLP) that promotes CD4(+) T cell homeostasis and contributes to allergic and inflammatory responses. TSLPR is a heterodimeric complex, consisting of the IL-7R-alpha chain and a common gamma-like receptor chain. The protein contains two fibronectin type III-like domains, four conserved cysteine residues, and a WSXWS box-like motif at its N-terminal, while the C-terminal intracellular region contains box 1 and box 2-like motifs. The protein is usually expressed in liver, kidney, heart, and skeletal muscle. The gene for human TSLPR is localized to the pseudoautosomal region, Xp22.3 and Yp11.3.
• Synonyms: CRL2; CRLF2Y; TSLPR

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway