CHRFAM7A Rabbit Polyclonal Antibody
Other products for "CHRFAM7A"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-CHRFAM7A antibody: synthetic peptide directed towards the middle region of human CHRFAM7A. Synthetic peptide located within the following region: DSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLN |
Formulation | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. Note that this product is shipped as lyophilized powder to China customers. |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 35 kDa |
Gene Name | CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion |
Database Link | |
Background | The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses.The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene fromThe family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, forThis hybrid gene.The N-terminally truncated products predicted byThe largest open reading frames for each variant would lackThe majority ofThe neurotransmitter-gated ion-channel ligand binding domain but retainThe transmembrane region that formsThe ion channel. Although current evidence supports transcription ofThis hybrid gene, translation ofThe nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq, Jul 2008] |
Synonyms | CHRNA7; CHRNA7-DR1; D-10 |
Note | Immunogen Sequence Homology: Dog: 100%; Pig: 100%; Rat: 100%; Horse: 100%; Human: 100%; Bovine: 100%; Rabbit: 100%; Guinea pig: 100%; Mouse: 93%; Zebrafish: 85% |
Reference Data | |
Protein Families | Druggable Genome, Ion Channels: Other, Transmembrane |
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in shipping.