GRK2 Mouse Monoclonal Antibody [Clone ID: 3F8-G6-C11]
Frequently bought together (3)
Transient overexpression lysate of adrenergic, beta, receptor kinase 1 (ADRBK1)
USD 396.00
Other products for "GRK2"
Specifications
Product Data | |
Clone Name | 3F8-G6-C11 |
Applications | WB |
Recommended Dilution | WB: 1:500 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | The immunogen for ADRBK1 antibody: purified recombinant human GRK2 protein fragments expressed in E.coli. |
Formulation | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol |
Purification | Affinity purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 80 kDa |
Gene Name | G protein-coupled receptor kinase 2 |
Database Link | |
Background | The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008] |
Synonyms | ADRBK1; BARK1; BETA-ARK1 |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Chemokine signaling pathway, Endocytosis |
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