BTK Mouse Monoclonal Antibody [Clone ID: 5B12-C9-F10]
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Specifications
Product Data | |
Clone Name | 5B12-C9-F10 |
Applications | WB |
Recommended Dilution | WB: 1:1000 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | The immunogen for BTK antibody: purified recombinant human BTK protein fragments expressed in E.coli. |
Formulation | Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol. |
Purification | Affinity purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 77 kDa |
Gene Name | Bruton tyrosine kinase |
Database Link | |
Background | The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Synonyms | AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Primary immunodeficiency |
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