KDM5C Mouse Monoclonal Antibody [Clone ID: 2E4-E1-G8]

CAT#: TA346985

Mouse Monoclonal KDM5C / Jarid1C / SMCX Antibody

Specifications

Product Data

• Clone Name: 2E4-E1-G8
• Applications: IF, WB
• Recommended Dilution: WB: 1:1000, IF: 1:150
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: The immunogen for KDM5C antibody: purified recombinant human KDM5C / Jarid1C / SMCX protein fragments expressed in E.coli
• Formulation: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 220 kDa
• Gene Name: lysine demethylase 5C
• Database Link:
  NP_004178
  Entrez Gene 8242 Human
  UniProt ID P41229
• Background: This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked mental retardation. Alternative splicing results in multiple transcript variants.
• Synonyms: DXS1272E; JARID1C; MRX13; MRXJ; MRXSCJ; MRXSJ; SMCX; XE169
• Note: Detects ~38kDa. Can run up to 45kDa on SDS Page

Reference Data

• Protein Families: Druggable Genome, Transcription Factors