STAT1 Mouse Monoclonal Antibody [Clone ID: 6C2-F7-D12]

CAT#: TA347057

Mouse Monoclonal STAT1 Antibody

Specifications

Product Data

• Clone Name: 6C2-F7-D12
• Applications: IP, WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human, Monkey
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: The immunogen for STAT1 antibody: purified recombinant human STAT1 protein fragments expressed in E.coli
• Formulation: Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide,0.1mg/mlBSA and 50% glycerol.
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 91 kDa
• Gene Name: signal transducer and activator of transcription 1
• Database Link:
  NP_009330
  Entrez Gene 693650 MonkeyEntrez Gene 6772 Human
  UniProt ID P42224
• Background: The protein encoded by this gene is a member of the STAT protein family.In response to cytokines and growth factors,STAT family members are phosphorylated by the receptor associated kinases,and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.This protein can be activated by various ligands including interferon-alpha,interferon-gamma,EGF,PDGF and IL6.This protein mediates the expression of a variety of genes,which is thought to be important for cell viability in response to different cell stimuli and pathogens.Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq,Jul 2008]
• Synonyms: CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Chemokine signaling pathway, Jak-STAT signaling pathway, Pancreatic cancer, Pathways in cancer, Toll-like receptor signaling pathway