XRCC1 Mouse Monoclonal Antibody [Clone ID: 3F6-G7-F7]

CAT#: TA347071

Mouse Monoclonal XRCC1 Antibody

Specifications

Product Data

• Clone Name: 3F6-G7-F7
• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: The immunogen for XRCC1 antibody: purified recombinant human XRCC1 protein fragments expressed in E.coli.
• Formulation: Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 82 kDa
• Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 1
• Database Link:
  NP_006288
  Entrez Gene 7515 Human
  UniProt ID P18887
• Background: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents.This protein interacts with DNA ligase III,polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway.It may play a role in DNA processing during meiogenesis and recombination in germ cells.A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq,Jul 2008]
• Synonyms: RCC

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Base excision repair