Ku70 (XRCC6) Mouse Monoclonal Antibody [Clone ID: 7B1-E12-G4]

CAT#: TA347073

Mouse Monoclonal Ku70 Antibody

Specifications

Product Data

• Clone Name: 7B1-E12-G4
• Applications: IF, IP, WB
• Recommended Dilution: WB: 1:1000, IF: 1:200
• Reactivities: Human, Monkey
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: The immunogen for XRCC6 antibody: purified recombinant human Ku70 protein fragments expressed in E.coli.
• Formulation: Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 67 kDa
• Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 6
• Database Link:
  NP_001460
  Entrez Gene 2547 Human
  UniProt ID P12956
• Background: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]
• Synonyms: CTC75; CTCBF; G22P1; KU70; ML8; TLAA

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Non-homologous end-joining