H3FA (HIST1H3A) Rabbit Polyclonal Antibody
Frequently bought together (2)
Other products for "H3C1"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | Western blotting (1:750); ChIP (1 - 5 µl/ChIP) |
Reactivities | Drosophila, Human, Mouse |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-H3K9me3 antibody: the region of histone H3 containing the trimethylated lysine 9 (H3K9me3). |
Concentration | lot specific |
Purification | Whole antiserum from rabbit containing 0.05% azide. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | histone cluster 1, H3a |
Database Link | |
Background | Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called "histone code". Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases. Trimethylation of histone H3K9 is associated with inactive regions. |
Synonyms | A; H3; H3FA |
Reference Data | |
Protein Pathways | Systemic lupus erythematosus |
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