XRCC1 Rabbit Polyclonal Antibody

CAT#: TA347508

Rabbit Polyclonal Anti-XRCC1 Antibody

Product Images

Western blot analysis on Jurkat, COS7 and HuvEc cell lysate using XRCC1 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-XRCC1 Antibody: A synthesized peptide derived from human XRCC1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 90 kDa
• Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 1
• Database Link:
  NP_006288
  Entrez Gene 22594 MouseEntrez Gene 84495 RatEntrez Gene 7515 Human
  UniProt ID P18887
• Background: XRCC1 Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Homodimer. Interacts with polynucleotide kinase (PNK), DNA polymerase-beta (POLB) and DNA ligase III (LIG3).
• Synonyms: RCC
• Note: XRCC1 antibody detects endogenous levels of total XRCC1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Base excision repair