MAN1B1 Rabbit Polyclonal Antibody

CAT#: TA347576

Rabbit Polyclonal Anti-MAN1B1 Antibody

Product Images

Western blot analysis on 3T3 cell lysate using MAN1B1 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-MAN1B1 Antibody: A synthesized peptide derived from human MAN1B1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 80 kDa
• Gene Name: mannosidase alpha class 1B member 1
• Database Link:
  NP_057303
  Entrez Gene 11253 Human
  UniProt ID Q9UKM7
• Background: MAN1B1 Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations, as found in the ER quality control compartment (ERQC)
• Synonyms: ERMAN1; ERManI; MANA-ER; MRT15
• Note: MAN1B1 antibody detects endogenous levels of total MAN1B1

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Metabolic pathways, N-Glycan biosynthesis