LRAT Rabbit Polyclonal Antibody
Frequently bought together (2)
Transient overexpression lysate of lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) (LRAT)
USD 396.00
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Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 1:500-1:2000 |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-LRAT Antibody: A synthesized peptide derived from human LRAT |
Formulation | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt |
Concentration | lot specific |
Purification | Immunogen affinity purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 27 kDa |
Gene Name | lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) |
Database Link | |
Background | LRAT Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters. Retinyl esters are storage forms of vitamin A. LRAT plays a critical role in vision. It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments. Belongs to the H-rev107 family. LRAT activity is up-regulated by dietary vitamin A. |
Synonyms | LCA14 |
Note | LRAT Antibody detects endogenous levels of LRAT |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Retinol metabolism |
Documents
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FAQs |
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