MMP2 Rabbit Polyclonal Antibody

CAT#: TA347674

Rabbit Polyclonal Anti-MMP2 Antibody

Product Images

Western blot analysis on LOVO cell lysate using MMP2 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-MMP2 Antibody: A synthesized peptide derived from human MMP2
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 74 kDa
• Gene Name: matrix metallopeptidase 2
• Database Link:
  NP_004521
  Entrez Gene 17390 MouseEntrez Gene 81686 RatEntrez Gene 4313 Human
  UniProt ID P08253
• Background: MMP2 Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways.
• Synonyms: CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1
• Note: MMP2 Antibody detects endogenous levels of MMP2

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Bladder cancer, GnRH signaling pathway, Leukocyte transendothelial migration, Pathways in cancer