DNA polymerase alpha (POLA1) Rabbit Polyclonal Antibody

CAT#: TA347928

Rabbit Polyclonal Anti-DNA Polymerase a Antibody

Product Images

Western blot analysis of DNA Polymerase a expression in 293 cells

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-DNA Polymerase a Antibody: A synthesized peptide derived from human DNA Polymerase a
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 169 kDa
• Gene Name: polymerase (DNA) alpha 1, catalytic subunit
• Database Link:
  NP_058633
  Entrez Gene 5422 Human
  UniProt ID P09884
• Background: Plays an essential role in the initiation of DNA replication. During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1/p180, a regulatory subunit POLA2/p70 and two primase subunits PRIM1/p49 and PRIM2/p58) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1. POLA1/p180, a regulatory subunit POLA2/p70 and two primase subunits PRIM1/p49 and PRIM2/p58) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1.
• Synonyms: NSX; p180; POLA
• Note: DNA Polymerase a Antibody detects endogenous levels of total DNA Polymerase a

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: DNA replication, Metabolic pathways, Purine metabolism, Pyrimidine metabolism