Eph receptor B1 (EPHB1) Rabbit Polyclonal Antibody

CAT#: TA347929

Rabbit Polyclonal Anti-EPHB1 Antibody

Product Images

Western blot analysis of EPHB1 expression in COS7 cells

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-EPHB1 Antibody: A synthesized peptide derived from human EPHB1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 110 kDa
• Gene Name: EPH receptor B1
• Database Link:
  NP_004432
  Entrez Gene 24338 RatEntrez Gene 270190 MouseEntrez Gene 2047 Human
  UniProt ID P54762
• Background: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Cognate/functional ephrin ligands for this receptor include EFNB1, EFNB2 and EFNB3. During nervous system development
• Synonyms: ELK; EPHT2; Hek6; NET
• Note: EPHB1 Antibody detects endogenous levels of total EPHB1

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Axon guidance