BUB1 Rabbit Polyclonal Antibody

CAT#: TA347945

Rabbit Polyclonal Anti-BUB1 Antibody

Product Images

Western blot analysis of BUB1 expression in COLO205 cells

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-BUB1 Antibody: A synthesized peptide derived from human BUB1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 122 kDa
• Gene Name: BUB1 mitotic checkpoint serine/threonine kinase
• Database Link:
  NP_004327
  Entrez Gene 699 Human
  UniProt ID O43683
• Background: Serine/threonine-protein kinase that performs 2 crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Has a key role in the assembly of checkpoint proteins at the kinetochore, being required for the subsequent localization of CENPF, BUB1B, CENPE and MAD2L1
• Synonyms: BUB1A; BUB1L; hBUB1
• Note: BUB1 Antibody detects endogenous levels of total BUB1

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation