NOTCH2 Rabbit Polyclonal Antibody

CAT#: TA347961

Rabbit Polyclonal Anti-Notch 2 (Cleaved-Asp1733) Antibody

Product Images

Western blot analysis of Notch 2 (Cleaved-Asp1733) expression in293 cell extract treated with TNF-alpha

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Notch 2 (Cleaved-Asp1733) Antibody: A synthesized peptide derived from human Notch 2 (Cleaved-Asp1733)
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 110 kDa
• Gene Name: notch 2
• Database Link:
  NP_001186930
  Entrez Gene 18129 MouseEntrez Gene 29492 RatEntrez Gene 4853 Human
  UniProt ID Q04721
• Background: Synthesized in the endoplasmic reticulum as an inactive form which is proteolytically cleaved by a furin-like convertase in the trans-Golgi network before it reaches the plasma membrane to yield an active, ligand-accessible form. Cleavage results in a C-terminal fragment N(TM) and a N-terminal fragment N(EC)
• Synonyms: AGS2; HJCYS; hN2
• Note: Notch 2 (Cleaved-Asp1733) Antibody detects endogenous levels of total Notch 2 (Cleaved-Asp1733)

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Dorso-ventral axis formation, Notch signaling pathway