Ku70 (XRCC6) Rabbit Polyclonal Antibody
Frequently bought together (3)
Recombinant protein of human X-ray repair complementing defective repair in Chinese hamster cells 6 (XRCC6)
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Transient overexpression lysate of X-ray repair complementing defective repair in Chinese hamster cells 6 (XRCC6)
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Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 1:500-1:2000 |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-Ku70/80 Antibody: A synthesized peptide derived from human Ku70/80 |
Formulation | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt |
Concentration | lot specific |
Purification | Immunogen affinity purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 70, 82 kDa |
Gene Name | X-ray repair complementing defective repair in Chinese hamster cells 6 |
Database Link | |
Background | The Ku autoantigen is a heterodimer of 70kDa (p70) and 80kDa (p80) proteins. The p70 / p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. The Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis. |
Synonyms | CTC75; CTCBF; G22P1; KU70; ML8; TLAA |
Note | Ku70/80 Antibody detects endogenous levels of total Ku70/80 |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Non-homologous end-joining |
Documents
Product Manuals |
FAQs |
SDS |
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