HNRNPD Rabbit Polyclonal Antibody

CAT#: TA348425

Rabbit Polyclonal Anti-Phospho-hnRPD(Ser83) Antibody

Product Images

Western blot analysis on HuvEc cell lysate using Phospho-hnRPD (Ser83) Antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Phospho-hnRPD(Ser83) Antibody: A synthesized peptide derived from human hnRPD around the phosphorylation site of Sersine 83
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 38 kDa
• Gene Name: heterogeneous nuclear ribonucleoprotein D
• Database Link:
  NP_112737
  Entrez Gene 11991 MouseEntrez Gene 79256 RatEntrez Gene 3184 Human
  UniProt ID Q14103
• Background: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.
• Synonyms: AUF1; AUF1A; hnRNPD0; HNRPD; P37
• Note: Phospho-hnRPD(Ser83) Antibody detects endogenous levels of hnRPD only when phosphorylated at Sersine 83

Reference Data

• Protein Families: Druggable Genome, Transcription Factors