BTK Rabbit Polyclonal Antibody

CAT#: TA348449

Rabbit Polyclonal Anti-Phospho-BTK(Tyr223) Antibody

Product Images

Western blot analysis on HeLa cell lysate using Phospho-BTK (Tyr223) Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Phospho-BTK(Tyr223) Antibody: A synthesized peptide derived from human BTK around the phosphorylation site of Tyrosine 223
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 80 kDa
• Gene Name: Bruton tyrosine kinase
• Database Link:
  NP_000052
  Entrez Gene 12229 MouseEntrez Gene 367901 RatEntrez Gene 695 Human
  UniProt ID Q06187
• Background: Defects in the Bruton tyrosine kinase (BTK) gene cause Agammaglobulinemia. Agammaglobulinemia is an X-linked immunodeficiency characterized by failure to produce mature B lymphocyte cells and associated with a failure of Ig heavy chain rearrangement. [provided by RefSeq]
• Synonyms: AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA
• Note: Phospho-BTK(Tyr223) Antibody detects endogenous levels of BTK only when phosphorylated at Tyrosine 223

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Primary immunodeficiency