PINK1 Rabbit Polyclonal Antibody

CAT#: TA349069

Rabbit Polyclonal Anti-PDCL3 Antibody


USD 484.00

5 Days*

Size
    • 100 ug

Product Images

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Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen PDCL3 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human PDCL3.
Formulation PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification PDCL3 antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size Predicted: 26 kDa; Observed: 25 kDa
Gene Name PTEN induced putative kinase 1
Background Phosducin-like proteins (PhLPs) are a conserved family of proteins with thioredoxin-like domains that were initially identified as modulators of G protein signaling (1,2). PDCL3 is highly homologous to PDCL and shares an N-terminal helix domain and a C-terminal thioredoxin-fold (Trx-fold) domain (3). Along with the related protein PDCL2, PDCL3 interacts with the chaperonin CCT and modulates CCT-mediated actin and tubulin folding (4). Modulation of PDCL3 levels by MAPK phosphorylation and RhoA-dependent changes also promote cytoskeletal remodeling (5).
Synonyms BRPK; PARK6
Reference Data
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Parkinson's disease

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.