HDAC2 Rabbit Polyclonal Antibody
Frequently bought together (2)
Transient overexpression lysate of histone deacetylase 2 (HDAC2)
USD 605.00
Other products for "HDAC2"
Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommended Dilution | WB: 0.5 - 1 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | HDAC2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human HDAC2. |
Formulation | PBS containing 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | HDAC2 antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | Predicted: 54 kDa; Observed: 52 kDa |
Gene Name | histone deacetylase 2 |
Database Link | |
Background | The histone deacetylase (HDAC) family contains multiple members which are divided into four classes. Class I of the HDAC family comprises four members, HDAC1, 2, 3, and 8, each of which contains a deacetylase domain and exhibits a different, individual substrate specificity and function in vivo (1). HDAC2 was first identified as as a mammalian homolog to the yeast transcriptional regulator RPD3 (2). HDAC2 forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor (2,3). Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events (4). |
Synonyms | HD2; RPD3; YAF1 |
Reference Data | |
Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
Protein Pathways | Cell cycle, Chronic myeloid leukemia, Huntington's disease, Notch signaling pathway, Pathways in cancer |
Documents
Product Manuals |
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