EPLIN (LIMA1) Rabbit Polyclonal Antibody

CAT#: TA349079

Rabbit Polyclonal Anti-SOX18 Antibody

Product Images

Western blot analysis of SOX18 in 3T3 cell lysate with SOX18 antibody at 1 ug/mL.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SOX18 antibody was raised against a 17 amino acid peptide near the amino terminus of human SOX18.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: SOX18 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 42 kDa; Observed: 44 kDa
• Gene Name: LIM domain and actin binding 1
• Database Link:
  NP_057441
  Entrez Gene 65970 MouseEntrez Gene 300228 RatEntrez Gene 51474 Human
  UniProt ID Q9UHB6
• Background: SOX18 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate (1,2). SOX18 is part of the SoxF subgroup which plays an important role in the differentiation of different cell types (3). SOX is known to be involved with vascularization and endothelial development, suggesting that it may be useful as a potential target for inhibiting tumor angiogenesis (4). Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia (5).
• Synonyms: EPLIN; SREBP3