KIRREL 3 (KIRREL3) Rabbit Polyclonal Antibody

CAT#: TA349103

Rabbit Polyclonal Anti-KIRREL3 Antibody

Product Images

Western blot analysis of KIRREL3 in mouse kidney tissue lysate with KIRREL3 antibody at (A) 1 and (B) 2 ug/mL.

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  Immunohistochemistry of KIRREL3 in mouse kidney tissue with KIRREL3 antibody at 5 ug/mL.

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  Immunofluorescence of KIRREL3 in mouse kidney tissue with KIRREL3 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: KIRREL3 antibody was raised against a 19 amino acid peptide near the amino terminus of human KIRREL3.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: KIRREL3 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 64, 84 kDa; Observed: 60 kDa
• Gene Name: kin of IRRE like 3 (Drosophila)
• Database Link:
  NP_115920
  Entrez Gene 67703 MouseEntrez Gene 315546 RatEntrez Gene 84623 Human
  UniProt ID Q8IZU9
• Background: KIRREL3, also known as nephrin-like protein 2, is a type I transmembrane protein belonging to a family of three podocin interacting proteins and the immunoglobulin superfamily (1). KIRREL3 is involved in the regulation of both glomerular and neural development (2), and more specifically, the nucleogenesis of the pontine nuclei in the developing hindbrain (3). KIRREL3 has also been shown to interact with the synaptic scaffold protein calmodulin-associated serine/threonine kinase (CASK) in neuronal cells (4).
• Synonyms: KIRRE; MRD4; NEPH2; PRO4502

Reference Data

• Protein Families: Transmembrane