KCNK1 Rabbit Polyclonal Antibody

CAT#: TA349116

Rabbit Polyclonal Anti-KCNK1 Antibody

Product Images

Western blot analysis of KCNK1 in 3T3 cell lysate with KCNK1 antibody at 1 ug/mL.

• 

  Immunohistochemistry of KCNK1 in mouse brain tissue with KCNK1 antibody at 5 ug/mL.

• 

  Immunofluorescence of KCNK1 in mouse brain tissue with KCNK1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: KCNK1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human KCNK1.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: KCNK1 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 37 kDa; Observed: 35 kDa
• Gene Name: potassium two pore domain channel subfamily K member 1
• Database Link:
  NP_002236
  Entrez Gene 16525 MouseEntrez Gene 59324 RatEntrez Gene 3775 Human
  UniProt ID O00180
• Background: The potassium channel, subfamily K, member 1 (KCNK1), is member of the superfamily of potassium channel proteins containing two pore-forming P domains (1,2). KCNK1 is a ubiquitous human weakly inward rectifying K+ channel that is widely expressed in human tissues, and particularly abundant in brain and heart (1). Both KCNK1 and the related protein KCNK2 contribute significantly to the passive conductance of hippocampal astrocytes (3).
• Synonyms: DPK; HOHO; K2P1; K2p1.1; KCNO1; TWIK-1; TWIK1

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane