ATG4A Rabbit Polyclonal Antibody
Frequently bought together (2)
Transient overexpression lysate of ATG4 autophagy related 4 homolog A (S. cerevisiae) (ATG4A), transcript variant 2
USD 396.00
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Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommended Dilution | WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | NOSTRIN antibody was raised against a 17 amino acid peptide near the carboxy terminus of human NOSTRIN. |
Formulation | PBS containing 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | NOSTRIN antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | Predicted: 47, 53, 56, 62 kDa; Observed: 68 kDa |
Gene Name | autophagy related 4A cysteine peptidase |
Database Link | |
Background | NOSTRIN. also known as endothelial nitric oxide synthase traffic inducer, is a member of the Pombe Cdc15 homology (PCH) family of proteins which may function as the modulator of the subcellular localisation and activity of endothelial nitric oxide synthase (eNOS) (1,2). It decreases NOS3 activity by inducing its translocation away from the plasma membrane (3). NOSTRIN typically exists as a trimer and is expressed in the vascular endothelial cells of highly vascularized tissues such as placenta, lung, kidney and heart. NOSTRIN is necessary for proper vascular development in zebrafish and postnatal retinal angiogenesis in mice (4,5). |
Synonyms | APG4A; AUTL2 |
Reference Data | |
Protein Families | Protease |
Protein Pathways | Regulation of autophagy |
Documents
Product Manuals |
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