KIRREL 3 (KIRREL3) Rabbit Polyclonal Antibody

CAT#: TA349140

Rabbit Polyclonal Anti-GLIS2 Antibody

Product Images

Western blot analysis of GLIS2 in K562 cell lysate with GLIS2 antibody at 1 ug/mL.

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  Immunohistochemistry of GLIS2 in mouse kidney tissue with GLIS2 antibody at 5 ug/mL.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: GLIS2 antibody was raised against an 18 amino acid peptide near the center of human GLIS2.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: GLIS2 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 58 kDa; Observed: 60 kDa
• Gene Name: kin of IRRE like 3 (Drosophila)
• Database Link:
  NP_115920
  Entrez Gene 67703 MouseEntrez Gene 315546 RatEntrez Gene 84623 Human
  UniProt ID Q8IZU9
• Background: GLIS2, also known as neuronal Krueppel-like, is a 524 amino acid protein that belongs to the GLI C2H2-type zinc-finger protein family (1). GLIS2 can act either as a transcription repressor or as a transcription activator and may be involved in neuron differentiation (1,2). GLIS2 is expressed at high levels in kidney and at low levels in heart, lung and placenta. Mutations of GLIS2 have been suggested to be associated with development of progressive chronic kidney disease with characteristics resembling nephronophthisis (3,4).
• Synonyms: KIRRE; MRD4; NEPH2; PRO4502

Reference Data

• Protein Families: Transmembrane