PTPN5 Rabbit Polyclonal Antibody

CAT#: TA349163

Rabbit Polyclonal Anti-RSPO3 Antibody

Product Images

Western blot analysis of RSPO3 in 293 cell lysate with RSPO3 antibody at 1 ug/mL.

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  Immunocytochemistry of RSPO3 in 293 cells with RSPO3 antibody at 5 ug/mL.

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  Immunofluorescence of RSPO3 in 293 cells with RSPO3 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: RSPO3 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human RSPO3.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: RSPO3 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 30 kDa; Observed: 30 kDa
• Gene Name: protein tyrosine phosphatase, non-receptor type 5
• Database Link:
  NP_116170
  Entrez Gene 19259 MouseEntrez Gene 84867 Human
  UniProt ID P54829
• Background: RSPO3 is a member of the R-spondin family and plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis (1,2). RSPO3 has been shown to be involved in regulating the balance between angioblast and blood cell specification during embryonic vasculogenesis and angiogenesis and may be involved in tumor development (3,4).
• Synonyms: PTPSTEP; STEP

Reference Data

• Protein Families: Druggable Genome, Phosphatase, Transmembrane
• Protein Pathways: MAPK signaling pathway